The pride of St Louis is the city's clean, efficient light rail system called the MetroLink, regarded as one of the best mass transit systems in the United States. Using the MetroLink, visitors can see most of St Louis' attractions without a car.

The system's zone covers the airport and East St Louis, stretching through downtown. Trains stop at multiple stations in Missouri and Illinois before the line ends at Shiloh-Scott. A basic MetroLink fare is $2.50.

The MetroBus network, which covers not only the city but also most of the county, also serves St Louis. Buses run to schedule from about 4am until after midnight. A basic bus fare is $2. There are taxi ranks near most major hotels and attractions in the city, while cabs can be ordered from various companies.

Those who opt for self-driving will find the city easy to navigate, as the downtown streets are laid out in a grid pattern and there is also a good network of highways. There is abundant parking in high-rise garages.